Two celebrated essays on the comic, reprinted together with a long appendix written for this volume by the editor. The appendix itself, bulging with learned references, is a comprehensive essay on the place of comedy in the human situation, past and present.--V. G. C.

Professional caregivers who work with the trauma and suffering of others, such as doctors, nurses and psychologists, may face significant challenges along with the risk of adverse, long-term mental and physical health problems. Caregivers with responsibility for dependants outside their professional work reported more stress. This finding is of particular relevance in respect of caregivers in under-developed countries such as Zimbabwe, where many households have taken in additional children who have been orphaned, whose parents are ill, or whose parents have (...) temporarily gone elsewhere in search of work. For the purposes of the study, a qualitative phenomenological research design was selected as appropriate to the focus on human experience. An interpretative approach was adopted to explore and explicate the lived experiences of the participants and the meaning they attached to them. The major sources of stress for professional caregivers emerged as being resource constraints, interpersonal issues, and personal issues. Factors found to promote coping include the caregiver’s meaning making perspective, making a difference, and constructing a sense of personal control. (shrink)

A large proportion of hospital inpatients are affected by cognitive impairment, posing challenges in the provision of their care in busy, fast-paced acute wards. Signs and symbols, known as visual identifiers, are employed in many U.K. hospitals with the intention of helping healthcare professionals identify and respond to the needs of these patients. Although widely considered useful, these tools are used inconsistently, have not been subject to full evaluation, and attract criticism for acting as a shorthand for a routinized response. (...) In order for visual identifiers to be used effectively in acute care settings, thorough consideration must be given to the ethical and legal issues that are engaged in this context, and their potential benefits and harms must be weighed and balanced. This paper proposes a set of legal and ethical principles that can be used to guide the implementation of visual identifiers. Together, these principles provide a framework applicable in the design and implementation phases to systematically identify relevant considerations arising from the use of these tools. We outline some tensions that arise between principles and conclude that selecting a preferred moral framework could help to guide decision-making, as does clarity around the purpose and objectives of the identifier. (shrink)

The phase φ of any wave is determined by the ratio x/λ consisting of the distance x propagated by the wave and its wavelength λ. Hence, the dependence of φ on λ constitutes an analogue system for the mathematical operation of division, that is to obtain the hyperbolic function f(ξ)≡1/ξ. We take advantage of this observation to decompose integers into primes and implement this approach towards factorization of numbers in a multi-path Michelson interferometer. This work is part of a larger (...) program geared towards unraveling the connections between quantum mechanics and number theory. We briefly summarize this aspect. (shrink)

The geometry of the state space of a finite-dimensional quantum mechanical system, with particular reference to four dimensions, is studied. Many novel features, not evident in the two-dimensional space of a single spin, are found. Although the state space is a convex set, it is not a ball, and its boundary contains mixed states in addition to the pure states, which form a low-dimensional submanifold. The appropriate language to describe the role of the observer is that of flag manifolds.

The article compares views of C.G. Jung and N.O. Lossky on the nature of time, including in the context of contemporary to them physical theories - quantum mechanics by W. Pauli and relativistic physics by A. Einstein. In particular, the author points to the similarity of ideas of both thinkers that the psyche relativizes time not only subjectively, but also objectively. Jung and Lossky provide this statement with a similar empirical basis, for example, the researches of T. Flournoy, as well (...) as similar theoretical arguments by postulating a fundamental acausal principle of the connection of all things, which is better suited for describing psychic and some physical phenomena than the classical causal explanation. In analytical psychology, such a principle is synchronicity, in hierarchical personalism - gnoseological coordination. Both concepts are genetically related to the G.W. Leibniz idea of pre-established harmony, which was reinterpreted by Jung and Lossky through different worldview foundations. Jung in his reasoning relied on the transcendental idealism of I. Kant, the principle of complementarity and the discoveries of quantum mechanics, Lossky - on intuitivism, the principle of subordination and on his own interpretation of Einsteins theories. Jung comes to the conclusion that the psyche has a timeless character, and Lossky comes to the conclusion that it has a super-temporal character. Jungs timelessness indicates the transcendental nature of psyche and the strive to get away from the classical causal explanation, saving it according to the principle of complementarity only to consider the phenomenal side of being and mainly physical processes. One of the pioneers of quantum mechanics Pauli was of the same opinion in general. Because of there is nothing transcendent in hierarchical personalism, Losskys super-temporality is of a strive to find a deeper basis for occurring in time processes, and, according to the principle of subordination, to include time in the hierarchical structure of the universe, prescribing for it a role of one of the two key forms of psychic and psycho-material processes characteristic of a certain stage of being. (shrink)

In this paper we consider an intuitionistic variant of the modal logic S4 (which we call IS4). The novelty of this paper is that we place particular importance on the natural deduction formulation of IS4— our formulation has several important metatheoretic properties. In addition, we study models of IS4— not in the framework of Kirpke semantics, but in the more general framework of category theory. This allows not only a more abstract definition of a whole class of models but also (...) a means of modelling proofs as well as provability. (shrink)

BackgroundNo standard method exists to assess how many consults a healthcare ethics consultation (HCEC) service should perform. To address this, we developed a method to estimate the volume of HCEC services based on a mixed-methods approach that included a systematic review and survey data on the volume of consult services requested.MethodsOur investigation included a systematic review of studies that reported the volume of HCEC services that were requested from 2000 to 2017, institutional surveys, and statistical analyses that estimated the volume (...) of HCEC services that were adjusted to the size of the hospitals in the survey and to population acuity.ResultsWe contacted the authors of 19 studies that met our inclusion criteria; 17 authors responded to the institutional survey and five provided annualized data points. We found that standard methods of reporting the volume of HCEC services led to inaccuracies in estimating the growth of HCEC services over time. To rectify this, we proposed two means to estimate volume based on either the service goals of HCEC services or hospital size and acuity.DiscussionThe statistical limitations of our study highlight the need to standardize the sharing and reporting of data in clinical ethics. Future work should further standardize methods of HCEC quality assessment using measures similar to those we describe. (shrink)

The biological sciences study (bio)complex living systems. Research directed at the mechanistic explanation of the "live" state truly requires a pluralist research program, i.e. BioComplexity research. The program should apply multiple intra-level and inter-level theories and methodologies. We substantiate this thesis with analysis of BioComplexity: metabolic and modular control analysis of metabolic pathways, emergence of oscillations, and the analysis of the functioning of glycolysis.

In this paper, the Helmholtz equation with quadratic damping themes is used for modeling the dynamics of a simple prey-predator system also called a simple Lotka–Volterra system. From the Helmholtz equation with quadratic damping themes obtained after modeling, the equilibrium points have been found, and their stability has been analyzed. Subsequently, the harmonic oscillations have been studied by the harmonic balance method, and the phenomena of resonance and hysteresis are observed. The primary and secondary resonances have been researched by the (...) multiple-scale method, and the conditions of stability of the amplitudes of oscillations are determined. Chaos is detected analytically by the Melnikov method and numerically using the basin of attraction, the bifurcation diagram, the Lyapunov exponent, the phase portrait, and the Poincaré section. The effects of all the parameters of the system are analyzed in detail, and special emphasis is placed on the new parameters. Through this analysis, the complex phenomena such as hysteresis, bistability, amplitude jump, resonances, and chaos have been obtained. The control of the parameters and the necessary conditions to control the aforementioned phenomena have been found. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)